Bolivia has a temperate climate but with wide differences between day and night. The wettest period is November to March, which, in extreme circumstances, may induce landslides in mountainous areas, and cause certain roads to become impassable. The northeast slopes of the Andes are semi-tropical. Visitors often find La Paz uncomfortable because of the thin air due to high altitude. The mountain areas can become very cold at night.

Lightweight linens with a raincoat. A light overcoat is necessary at night, particularly in the Altiplano and the Puna.